Protoporphyrin IX: the Good, the Bad, and the Ugly
نویسندگان
چکیده
منابع مشابه
Protoporphyrin IX: the Good, the Bad, and the Ugly.
Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme. PPIX has some biologic functions of its own, and PPIX-based strategies have been used for cancer diagnosis and treatment (the good). PPIX serves as the substrate for ferrochelatase, the final enzyme in heme biosynthesis, and its homeostasis is tightly regulated during heme synthesis. Ac...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2015
ISSN: 1521-0103
DOI: 10.1124/jpet.115.228130